• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human LEFTY-1 protein


Typically ≤ 2.5 µg/mL EC50

Species Reactivity




Cat No : HZ-1109

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LEFTB, LEFTY1, LEFTYB, Protein lefty 1, Protein lefty B

Technical Specifications

GeneID 10637
Species Human
Expression HEK293
Activity Typically ≤ 2.5 µg/mL EC50
Purity >95%
Endotoxin<1 EU/μg
Accession NumberO75610
Molecular Mass 38 kDa, monomer, glycosylated
Formulation 10 mM Tris pH 7.4 + 450 mM NaCl + 1% CHAPS, See Certificate of Analysis for details
Species Reactivity human,mouse

Stability and Reconstitution

Stability and Storage Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile water containing 0.1% endotoxin-free recombinant human serum albumin (HSA).


LEFTY-1 is a member of the TGF-beta family of proteins that plays a role in left-right asymmetry determination of organ systems during development. LEFTY-1 regulates transforming growth factor, mitogen-activated protein kinase and other signaling pathways, and is considered to have a potential anti-inflammatory function (PMID: 29286065; 26316705; 10500184; 9708731)


LEFTB, LEFTY1, LEFTYB, Protein lefty 1, Protein lefty B



Stem Cells Dev

Lefty Glycoproteins in Human Embryonic Stem Cells: Extracellular Delivery Route and Posttranslational Modification in Differentiation.

Authors - ZhilaKhalkhali-Ellis