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Human CD86 Antibody Pair Set

Reactivity

Human

Range

78.1-5000 pg/mL

GeneID

942

Cat No : PA00100

Print datasheet

Synonyms

CD28LG2, LAB72, CTLA 4 counter receptor B7.2, Activation B7 2 antigen, B7 2, B70, FUN 1, CD86, CD86 molecule

验证数据展示

  • N/A

    Standard curve of PA00100 Human CD86 Antibody Pair Set.

产品信息

Product name Human CD86 Antibody Pair Set
Tests 10×96 well plate
Assay type Sandwich
Range 78.1-5000 pg/mL
Reactivity Human
Tested applications Sandwich ELISA
Gene ID (NCBI) 942
Specificity Please see the product datasheet
Entrez Gene ID 942(P42081)
Alternate Names CD28LG2, LAB72, CTLA 4 counter receptor B7.2, Activation B7 2 antigen, B7 2, B70, FUN 1, CD86, CD86 molecule

背景信息

CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin (Ig) superfamily. CD86 is primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages. CD86 has strong structural similarity with another B7 family molecule, CD80 (B7-1). CD86 and CD80 are the ligands for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte antigen 4 (CTLA-4). Binding of CD86 or CD80 with CD28 antigen is a costimulatory signal for T cell activation, proliferation, and cytokine production. Binding of CD86 or CD80 with CTLA-4 negatively regulates T cell activation and diminishes the immune response. CD86 and CD80 bind to CTLA-4 with higher affinity than CD28. Defects in CTLA-4-mediated transendocytosis of CD86 are associated with autoimmunity.

产品特性

  1. Optimization: The use of matched antibody pairs that have undergone rigorous screening and validation can significantly reduce the time required for development.
  2. Flexible Packaging: The availability of multiple specifications allows for the detection needs of various sample quantities to be met.
  3. Economic: This product offers cost-effective solutions for researchers who want to save on their budget while exploring unique sample detection systems in their assays.
  4. Natural Sample Testing: The product has undergone thorough testing using natural samples.

运输与储存

Shipping The product is shipped at 2-8℃. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store the unopened product at -20℃. Do not use past expiration date.