验证数据展示
产品信息
66768-1-PBS targets AGR2 in WB, IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Applications | WB, IHC, IF/ICC, IF-P, FC (Intra), Indirect ELISA Application Description |
Tested Reactivity | human, pig |
Immunogen | AGR2 fusion protein Ag2919 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | anterior gradient homolog 2 (Xenopus laevis) |
Synonyms | GOB 4, AGR 2, AG-2, AG2, AG 2 |
Calculated Molecular Weight | 175 aa, 20 kDa |
Observed Molecular Weight | 17 kDa |
GenBank Accession Number | BC015503 |
Gene Symbol | AGR2 |
Gene ID (NCBI) | 10551 |
RRID | AB_2882114 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | O95994 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.