Amylin Polyclonal antibody
Amylin Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, rat, mouse
Applications
IHC, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive IHC detected in | human pancreas tissue, mouse pancreas tissue, rat pancreas tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
22305-1-AP targets Amylin in IHC, ELISA applications and shows reactivity with human, rat, mouse samples.
| Tested Applications | IHC, ELISA Application Description |
| Tested Reactivity | human, rat, mouse |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | islet amyloid polypeptide |
| Synonyms | Amylin, DAP, Diabetes associated peptide, IAP, IAPP, islet amyloid polypeptide |
| Calculated Molecular Weight | 10 kDa |
| GenBank Accession Number | NM_000415 |
| Gene Symbol | Amylin |
| Gene ID (NCBI) | 3375 |
| RRID | AB_2879067 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | P10997 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring a tumor of the pancreas that is derived from beta cells and secretes INS. IAPP is co-secreted with INS by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
实验方案
| Product Specific Protocols | |
|---|---|
| IHC protocol for Amylin antibody 22305-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
