APC Anti-Mouse CD25/IL-2RA (PC61.5)

CD25/IL-2RA Monoclonal Antibody for FC
Cat No. APC-65137

产品说明书

CloneNo. PC61.5

宿主/亚型

Rat / IgG1, lambda

种属反应性

mouse

应用

FC

CD25, Il-2ra, Il2ra, IL-2R subunit alpha, Il2r

缓冲液配方:  PBS and Azide
PBS and Azide
规格: 

-/ -


经过测试的应用

Positive FC detected inanti-CD3/CD28 treated mouse splenocytes

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

FCSee 3 publications below

产品信息

APC-65137 targets CD25/IL-2RA in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
文献引用应用FC
经测试反应性 mouse
文献引用反应性mouse
免疫原 N/A 种属同源性预测
宿主/亚型 Rat / IgG1, lambda
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 2 receptor, alpha chain
别名 CD25, Il-2ra, Il2ra, IL-2R subunit alpha, Il2r
GenBank蛋白编号BC114437
基因名称 CD25
Gene ID (NCBI) 16184
RRIDAB_2883018
偶联类型 APC Fluorescent Dye
最大激发/发射波长650 nm / 660 nm
形式 Liquid
纯化方式Affinity purification
UNIPROT IDP01590
储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3
储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

背景介绍

Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells (PMID: 22585674).

实验方案

Product Specific Protocols
FC protocol for APC CD25/IL-2RA antibody APC-65137Download protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseFC

Phytomedicine

Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.

Authors - Li Wu
mouseFC

Acta Biomater

Injectable microenvironment-responsive hydrogels with redox-activatable supramolecular prodrugs mediate ferroptosis-immunotherapy for postoperative tumor treatment

Authors - Zhuo Cheng
mouseFC

J Neuroinflammation

27-hydroxycholesterol causes cognitive deficits by disturbing Th17/Treg balance and the related immune responses in mild cognitive impairment patients and C57BL/6J mice

Authors - Tao Wang
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