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Anti-Human CD44 (F10-44-2) Mouse IgG2a Recombinant Antibody, PBS Only

CD44 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

F10-44-2

Cat no : 65608-1-PBS

Print datasheet

Synonyms

Epican, ECMR-III, ECMR III, CSPG8, CDW44

验证数据展示

  • FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD44 Mouse IgG2a Recombinant Antibody (65608-1-MR, Clone: F10-44-2) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65608-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    FC experiment of human PBMCs using 65608-1-MR (same clone as 65608-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD44 Mouse IgG2a Recombinant Antibody (65608-1-MR, Clone: F10-44-2) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65608-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CD44 Ready-To-Use IHC Kit. CD44 primary antibody included.

产品信息

65608-1-PBS targets CD44 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen N/A 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Recombinant
Type Antibody
Full Name CD44 molecule (Indian blood group)
Synonyms Epican, ECMR-III, ECMR III, CSPG8, CDW44
Calculated Molecular Weight 742 aa, 82 kDa
GenBank Accession NumberBC004372
Gene Symbol CD44
Gene ID (NCBI) 960
ENSEMBL Gene IDENSG00000026508
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.