Anti-Human CD5 (L17F12)
CD5 Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG2a, kappa
Reactivity
Human
Applications
FC
Conjugate
Unconjugated
CloneNo.
L17F12
验证数据展示
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65200-1-Ig targets CD5 in FC applications and shows reactivity with Human samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | Human |
| Immunogen | Human T-cell acute lymphoblastic leukemia (T-ALL) cells 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | CD5 molecule |
| Synonyms | CD5, CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1 |
| Calculated Molecular Weight | 495 aa, 55 kDa |
| GenBank Accession Number | BC027901 |
| Gene Symbol | CD5 |
| Gene ID (NCBI) | 921 |
| ENSEMBL Gene ID | ENSG00000110448 |
| RRID | AB_2918469 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P06127 |
| Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD5 antibody 65200-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
