CRP Polyclonal antibody

CRP Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, WB,ELISA

Conjugate

Unconjugated

Cat No : 24175-1-AP

Print datasheet

Synonyms

C reactive protein, CRP, PTX1



经过测试的应用

Positive WB detected inserum from mouse injected with bacteria
Positive IHC detected inhuman liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

发表文章中的应用

WBSee 3 publications below

产品信息

The immunogen of 24175-1-AP is CRP Fusion Protein expressed in E. coli.

Tested Applications IHC, WB,ELISA
Cited Applications WB
Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CRP fusion protein Ag21466
Full Name C-reactive protein, pentraxin-related
Synonyms C reactive protein, CRP, PTX1
Calculated molecular weight 224 aa, 25 kDa
Observed molecular weight 25 kDa
GenBank accession numberBC125135
Gene symbol CRP
UniprotP02741
Gene ID (NCBI) 1401
RRIDAB_2879447
Conjugate Unconjugated
Form Liquid
Purification Method Antigen Affinity purified
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.

实验方案

Product Specific Protocols
WB protocol for CRP antibody 24175-1-APDownload protocol
IHC protocol for CRP antibody 24175-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle

Exp Ther Med

TLR4 gene in the regulation of periodontitis and its molecular mechanism.

Authors - Weijuan Qi
humanWB

Biomed Mater

Reversing cytotoxicity of uric acid by supramolecular encapsulation with acyclic cucurbit[n]uril.

Authors - Lingguang Kong
humanWB

J Proteome Res

Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease.

Authors - Yong Zhou
human, mouseWB

J Proteome Res

Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.

Authors - Shizhen Qin