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  • Featured Product
  • KD/KO Validated

MSH2 Monoclonal antibody, PBS Only

MSH2 Monoclonal Antibody for WB,IHC,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB,IHC,ELISA

Conjugate

Unconjugated

CloneNo.

2H5F5

Cat No : 60161-1-PBS

Print datasheet

Synonyms

COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2

验证数据展示

  • WB analysis of HeLa using 60161-1-Ig (same clone as 60161-1-PBS)

    WB analysis of HeLa using 60161-1-Ig (same clone as 60161-1-PBS)

    WB results of MSH2 (60161-1-Ig, 1:1000) antibody with si-Control and si-MSH2 transfected HeLa cells.. This data was developed using the same antibody clone with 60161-1-PBS in a different storage buffer formulation.

  • WB analysis using 60161-1-Ig (same clone as 60161-1-PBS)

    WB analysis using 60161-1-Ig (same clone as 60161-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60161-1-Ig (MSH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60161-1-PBS in a different storage buffer formulation.

  • WB analysis using 60161-1-Ig (same clone as 60161-1-PBS)

    WB analysis using 60161-1-Ig (same clone as 60161-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60161-1-Ig (MSH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60161-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 60161-1-Ig (same clone as 60161-1-PBS)

    IHC staining of human colon cancer using 60161-1-Ig (same clone as 60161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 60161-1-Ig (MSH2 Antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60161-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 60161-1-Ig (same clone as 60161-1-PBS)

    IHC staining of human colon cancer using 60161-1-Ig (same clone as 60161-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 60161-1-Ig (MSH2 Antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60161-1-PBS in a different storage buffer formulation.

产品信息

60161-1-PBS targets MSH2 in WB, IHC, ELISA applications and shows reactivity with human samples.

Tested Applications WB,IHC,ELISA Application Description
Tested Reactivity human
Immunogen MSH2 fusion protein Ag7835 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
Synonyms COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2
Calculated Molecular Weight 105 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC021566
Gene Symbol MSH2
Gene ID (NCBI) 4436
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP43246
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

背景介绍

MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell.