NCOR1 Polyclonal antibody

NCOR1 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA and More (2)

Conjugate

Unconjugated

Cat no : 20018-1-AP

Print datasheet

Synonyms

hCIT529I10, hN CoR, KIAA1047, N CoR, N CoR1, NCOR1, Nuclear receptor corepressor 1, TRAC1



经过测试的应用

Positive WB detected inHepG2 cells, K-562 cells
Positive IHC detected inhuman cervical cancer tissue, rat brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20018-1-AP targets NCOR1 in WB, IHC, IP, chIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, ELISA Application Description
Cited ApplicationsWB, IHC, IP, chIP
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name nuclear receptor co-repressor 1
Synonyms hCIT529I10, hN CoR, KIAA1047, N CoR, N CoR1, NCOR1, Nuclear receptor corepressor 1, TRAC1
Calculated Molecular Weight 270 kDa
Observed Molecular Weight 120 kDa
GenBank Accession NumberNM_006311
Gene Symbol NCOR1
Gene ID (NCBI) 9611
RRIDAB_10665360
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO75376
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

NCOR1, also named as KIAA1047 and TRAC1, belongs to the N-CoR nuclear receptor corepressors family. NCO1 mediates transcriptional repression by certain nuclear receptors. It is part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. The antibody recognizes the 103 kDa isoform of NCOR1.

实验方案

Product Specific Protocols
WB protocol for NCOR1 antibody 20018-1-APDownload protocol
IHC protocol for NCOR1 antibody 20018-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouse,humanWB

Nat Commun

Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease

Authors - Evangelia Lekka
chIP

PLoS Biol

Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.

Authors - Kenneth Allen Dyar
mouseWB

iScience

WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation

Authors - Kai Song
humanWB

Theranostics

Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease

Authors - Yan-Hang Wang
WB

Cell

Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

Authors - Jinjia Zhang
mouse,ratWB,IP,IHC

Cell Mol Life Sci

Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2

Authors - Kuang-Min Cheng
  • KO Validated