验证数据展示
产品信息
11616-1-AP targets RAB20 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IF |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | mouse |
| 免疫原 | RAB20 fusion protein Ag2193 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | RAB20, member RAS oncogene family |
| 别名 | RAB20, Ras related protein Rab 20 |
| 计算分子量 | 26 kDa |
| 观测分子量 | 26-29 kDa |
| GenBank蛋白编号 | BC026025 |
| 基因名称 | RAB20 |
| Gene ID (NCBI) | 55647 |
| RRID | AB_2877784 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9NX57 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RAB20 is a member of RAS oncogene family, it has no close relationship to any other members of RAB subfamily which consists of small GTP-binding proteins involved in the regulation of intracellullar vesicular transport. Firstly found highly expressed on the apical side of kidney tubuel epithelial cells, RAB20 was speculated to be involved in apical endocytosi and recylcing processes. So far, its function is not well known, however, RAB20 is recently found higher expressed in pancreatic adenocarcinomas than normal pancreas, which is proved by WB and IHC analyses, suggesting its promising role in diagnosis of pancreatic carcinogenesis. Catalog#11616-1-AP is a rabbit polyclonal antibody raised against full-length of human RAB20.
发表文章
| Species | Application | Title |
|---|---|---|
Cell Host Microbe A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity.
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J Cell Sci Identification of an immune-regulated phagosomal Rab cascade in macrophages.
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Mol Biol Cell Interferon-gamma-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages.
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Front Mol Neurosci Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction |