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验证数据展示

  • WB analysis of HEK-293T using 67884-1-Ig (same clone as 67884-1-PBS)

    WB analysis of HEK-293T using 67884-1-Ig (same clone as 67884-1-PBS)

    HEK-293T cells were subjected to SDS PAGE followed by western blot with 67884-1-Ig (ADC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67884-1-PBS in a different storage buffer formulation.

  • WB analysis using 67884-1-Ig (same clone as 67884-1-PBS)

    WB analysis using 67884-1-Ig (same clone as 67884-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67884-1-Ig (ADC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67884-1-PBS in a different storage buffer formulation.

  • WB analysis using 67884-1-Ig (same clone as 67884-1-PBS)

    WB analysis using 67884-1-Ig (same clone as 67884-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67884-1-Ig (ADC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67884-1-PBS in a different storage buffer formulation.

  • IF Staining of A431 using 67884-1-Ig (same clone as 67884-1-PBS)

    IF Staining of A431 using 67884-1-Ig (same clone as 67884-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using ADC antibody (67884-1-Ig, Clone: 1A2B11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67884-1-PBS in a different storage buffer formulation.

ADC Monoclonal antibody, PBS Only

ADC Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 67884-1-PBS

产品说明书

CloneNo. 1A2B11

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, pig, rat

应用

WB, IF/ICC, Indirect ELISA

别名

ADC, Antizyme inhibitor 2, ARGDC, arginine decarboxylase, AZI2, AZIN2, KIAA1945, ODC p, ODC paralogue, ODC1L, ODCP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67884-1-PBS targets ADC in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, pig, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 Human, mouse, pig, rat
免疫原 ADC fusion protein Ag31049 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 arginine decarboxylase
别名 ADC, Antizyme inhibitor 2, ARGDC, arginine decarboxylase, AZI2, AZIN2, KIAA1945, ODC p, ODC paralogue, ODC1L, ODCP
计算分子量 460 aa, 50 kDa
观测分子量48-50 kDa
GenBank蛋白编号BC028128
基因名称 ADC
Gene ID (NCBI) 113451
RRIDAB_2918641
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ96A70
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Antizyme inhibitor 2 (AZIN2) is a member of the antizyme inhibitor family, witch is able to bind to AZs and inhibit their action on both ODC activity and polyamine uptake. AZIN2 is predominantly expressed in the brain and testis and localized in the endoplasmic reticulum-golgi intermediate compartment. Available data suggest its role in cell growth, spermiogenesis, vesicular trafficking and secretion. Accumulation of azin2 has also been observed in brains of patients with Alzheimer's disease (PMID: 19832840) . AZIN2 has 5 described insoforms produced by alternative splicing. The molecular weight of AZIN2 is about 50 kDa.