验证数据展示
产品信息
66250-1-PBS targets C-Reactive Protein/CRP in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
经测试应用 | WB, IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat, pig |
免疫原 | C-Reactive Protein/CRP fusion protein Ag9883 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | C-reactive protein, pentraxin-related |
别名 | CRP, PTX1, C-reactive protein(1-205), C-Reactive Protein, C reactive protein |
计算分子量 | 224 aa, 25 kDa |
观测分子量 | 27 kDa |
GenBank蛋白编号 | BC020766 |
基因名称 | CRP |
Gene ID (NCBI) | 1401 |
RRID | AB_2881638 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P02741 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.