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验证数据展示

  • WB analysis of HeLa using 60262-1-Ig (same clone as 60262-1-PBS)

    WB analysis of HeLa using 60262-1-Ig (same clone as 60262-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 60262-1-Ig (IL1R2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60262-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 60262-1-Ig (same clone as 60262-1-PBS)

    IF Staining of HeLa using 60262-1-Ig (same clone as 60262-1-PBS)

    Immunofluorescent analysis of HeLa cells using 60262-1-Ig (IL1R2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). This data was developed using the same antibody clone with 60262-1-PBS in a different storage buffer formulation.

  • IF Staining of Jurkat using 60262-1-Ig (same clone as 60262-1-PBS)

    IF Staining of Jurkat using 60262-1-Ig (same clone as 60262-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using IL-1R2 antibody (60262-1-Ig, Clone: 3H4H4 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 60262-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

IL-1R2 Monoclonal antibody, PBS Only

IL-1R2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 60262-1-PBS

产品说明书

CloneNo. 3H4H4

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse

应用

WB, IF/ICC, Indirect ELISA

别名

IL1R2, 3H4H4, CD121 antigen-like family member B, CD121b, IL 1R 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

60262-1-PBS targets IL-1R2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag4495

Product name: Recombinant human IL-1R2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 24-347 aa of BC039031

Sequence: AARSCRFRGRHYKREFRLEGEPVALRCPQVPYWLWASVSPRINLTWHKNDSARTVPGEEETRMWAQDGALWLLPALQEDSGTYVCTTRNASYCDKMSIELRVFENTDAFLPFISYPQILTLSTSGVLVCPDLSEFTRDKTDVKIQWYKDSLLLDKDNEKFLSVRGTTHLLVHDVALEDAGYYRCVLTFAHEGQQYNITRSIELRIKKKKEETIPVIISPLKTISASLGSRLTIPCKVFLGTGTPLTTMLWWTANDTHIESAYPGGRVTEGPRQEYSENNENYIEVPLIFDPVTREDLHMDFKCVVHNTLSFQTLRTTVKEASST

种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 1 receptor, type II
别名 IL1R2, 3H4H4, CD121 antigen-like family member B, CD121b, IL 1R 2
计算分子量 398 aa, 45 kDa
观测分子量 45 kDa
GenBank蛋白编号BC039031
基因名称 IL1R2
Gene ID (NCBI) 7850
RRIDAB_2881383
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP27930
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.