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IL-1R2 Monoclonal antibody

IL-1R2 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 60262-1-Ig

产品说明书

CloneNo. 3H4H4

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse and More (1)

应用

WB, IF/ICC, ELISA and More (1)

IL1R2, IL 1RT 2, IL 1R beta, IL 1R 2, CD121b

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
CoraLite®594
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells
Positive IF/ICC detected inHeLa cells
Planning an IF experiment? We recommend our CoraLite®594 conjugated versions of this antibody.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)/ICCIF/ICC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

60262-1-Ig targets IL-1R2 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse
文献引用反应性human, mouse, rat
免疫原 IL-1R2 fusion protein Ag4495 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 1 receptor, type II
别名 IL1R2, IL 1RT 2, IL 1R beta, IL 1R 2, CD121b
计算分子量 398 aa, 45 kDa
观测分子量 45 kDa
GenBank蛋白编号BC039031
基因名称 IL1R2
Gene ID (NCBI) 7850
RRIDAB_2881383
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP27930
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.

实验方案

Product Specific Protocols
WB protocol for IL-1R2 antibody 60262-1-IgDownload protocol
IF protocol for IL-1R2 antibody 60262-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
ratWB

Mater Today Bio

Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis

Authors - Jingzhe Wang
mouseWB

Comput Struct Biotechnol J

Identification of potential diagnostic and prognostic biomarkers for sepsis based on machine learning

Authors - Li Ke
humanWB

J Pancreatol

Immune-related signature identifies IL1R2 as an immunological and prognostic biomarker in pancreatic cancer

Authors - Chengcheng Wang
  • KD Validated
mouseIF,WB

Biochem Pharmacol

Oridonin employs interleukin 1 receptor type 2 to treat noise-induced hearing loss by blocking inner ear inflammation

Authors - Meng-Bing Chen
mouseWB

Biomacromolecules

Biomimetic NO Scavenging Hyaluronic Acid Nanoparticles Enable Targeted Delivery of MTX and Integrated Management of Rheumatoid Arthritis

Authors - Yilin Liu
WB

Nat Commun

Targeted therapies of inflammatory diseases with intracellularly gelated macrophages in mice and rats

Authors - Cheng Gao
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