验证数据展示
经过测试的应用
Positive IF-P detected in | mouse eye tissue |
推荐稀释比
应用 | 推荐稀释比 |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-12833 targets Neuropeptide Y in IF-P applications and shows reactivity with human, mouse, rat samples.
经测试应用 | IF-P Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | Neuropeptide Y fusion protein Ag3568 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | neuropeptide Y |
别名 | CPON, Neuropeptide tyrosine, neuropeptide Y, NPY, PYY4 |
计算分子量 | 97 aa, 11 kDa |
GenBank蛋白编号 | BC029497 |
基因名称 | Neuropeptide Y |
Gene ID (NCBI) | 4852 |
RRID | AB_3083932 |
偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
最大激发/发射波长 | 493 nm / 522 nm |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P01303 |
储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer's disease by counteracting the toxic effect of β-amyloid in an in vitro model.
实验方案
Product Specific Protocols | |
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IF protocol for CL Plus 488 Neuropeptide Y antibody CL488-12833 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |