CoraLite® Plus 488-conjugated Neuropeptide Y Polyclonal antibody
Neuropeptide Y Polyclonal Antibody for IF-P
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF-P
Conjugate
CoraLite® Plus 488 Fluorescent Dye
验证数据展示
经过测试的应用
Positive IF-P detected in | mouse eye tissue |
For other applications, we recommend the unconjugated version of this antibody, 12833-1-AP
推荐稀释比
Application | Dilution |
---|---|
Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
CL488-12833 targets Neuropeptide Y in IF-P applications and shows reactivity with human, mouse, rat samples.
Tested Applications | IF-P Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | Neuropeptide Y fusion protein Ag3568 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | neuropeptide Y |
Synonyms | CPON, Neuropeptide tyrosine, neuropeptide Y, NPY, PYY4 |
Calculated Molecular Weight | 97 aa, 11 kDa |
GenBank Accession Number | BC029497 |
Gene Symbol | Neuropeptide Y |
Gene ID (NCBI) | 4852 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P01303 |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer's disease by counteracting the toxic effect of β-amyloid in an in vitro model.
实验方案
Product Specific Protocols | |
---|---|
IF protocol for CL Plus 488 Neuropeptide Y antibody CL488-12833 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |