- HEK293 expressed
- Endotoxin-free
- Animal-component free
HumanKine® recombinant human FGFbasic-TS protein
Cat No : HZ-1285
Synonyms
Basic fibroblast growth factor, BFGF, FGF basic, FGF basic-TS, FGF2, FGFB, FGFbasic, FGFbasic-TS, HBGF 2
Validation Data Gallery
Technical Specifications
GeneID | 2247 |
Species | Human |
Expression | HEK293 |
Activity | 0.05-0.4 ng/mL EC50 |
Purity | >95% |
Endotoxin | <1 EU/µg |
Accession Number | P09038 |
Molecular Mass | 17 kDa, monomer, non-glycosylated |
Formulation | 1x PBS, See Certificate of Analysis for details |
Species Reactivity | human,mouse |
Stability and Reconstitution
Stability and Storage | Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
Background
Basic Fibroblast growth factor (FGFbasic), also known as bFGF, FGF2, FGF-β or HBGF-2, belongs to the FGF family. FGF-basic is involved in a number of biological processes including embryonic development and differentiation, neuron differentiation, survival, and regeneration, and the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin (PMID 3272178, 3316527). FGF-basic is critical for human embryonic stem cells to remain in an undifferentiated state during cell culture (PMID 15782187).
Synonyms
Basic fibroblast growth factor, BFGF, FGF basic, FGF basic-TS, FGF2, FGFB, FGFbasic, FGFbasic-TS, HBGF 2
Publications
Species | Title |
---|---|
Protein Cell Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis. | |
Cell Stem Cell FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. | |
Int J Mol Sci β3-Adrenoreceptor Blockade Reduces Hypoxic Myeloid Leukemic Cells Survival and Chemoresistance. | |
Oxid Med Cell Longev Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress. | |
STAR Protoc Generation of PAX7 Reporter Cells to Investigate Skeletal Myogenesis from Human Pluripotent Stem Cells. |