验证数据展示
产品信息
69528-1-Ig targets Thrombopoietin in ELISA, Non-Neutralization applications and shows reactivity with Human samples.
| 经测试应用 | ELISA, Non-Neutralization Application Description |
| 经测试反应性 | Human |
| 免疫原 | human Humankine Thrombopoietin protein HZ-1248 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | thrombopoietin |
| 别名 | C mpl ligand, MGDF, MKCSF, ML, MPLLG, THPO, thrombopoietin, TPO |
| 基因名称 | Thrombopoietin |
| Gene ID (NCBI) | 7066 |
| RRID | AB_2923692 |
| 偶联类型 | Unconjugated |
| 形式 | Lyophilized Powder |
| 纯化方式 | Protein A purification |
| 储存缓冲液 | Sterile PBS , pH 7.4 |
| 内毒素 | <0.1 EU/μg |
| 复溶 | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| 稳定性与储存 | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
Thrombopoietin (TPO) is a primary regulator of megakaryocyte development and platelet production in mammals. Human TPO constitutively circulates and maintains thrombopoiesis through interaction with its cognate receptor, myeloproliferative leukemia protein(MPL). TPO also plays an important role in the maintenance and regulation of hematopoietic stem cells (HSCs).
This antibody is a neutralizing control antibody for THPO, the immunogen is the same as Neutrakine 69028-1-Ig but could not neutralize human TPO.