NeutraControl IL-12 p35 Monoclonal antibody
NeutraControl IL-12 p35 Monoclonal Antibody for ELISA, Non-Neutralization
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
ELISA, Non-Neutralization
Conjugate
Unconjugated
CloneNo.
2C4G2
验证数据展示
产品信息
69529-1-Ig targets IL-12 p35 in ELISA, Non-Neutralization applications and shows reactivity with Human samples.
| Tested Applications | ELISA, Non-Neutralization Application Description |
| Tested Reactivity | Human |
| Immunogen | human Humankine IL-12 p35 protein HZ-1256 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) |
| Synonyms | CLMF, CLMF p35, IL 12 subunit p35, IL 12A, IL-12 p35, IL12A, Interleukin 12 subunit alpha, NFSK, NKSF1, P35 |
| Gene Symbol | IL-12A |
| Gene ID (NCBI) | 3592 |
| Conjugate | Unconjugated |
| Form | Lyophilized Powder |
| Purification Method | Protein G purification |
| Storage Buffer | Sterile PBS. |
| Endotoxin | <0.1 EU/μg |
| Reconstitution | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
IL12 p35 is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of IFN-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
This antibody is a neutralizing control antibody for IL-12 p35, the immunogen is the same as Neutrakine 69029-1-Ig but could not neutralize human IL-12 p35.
This antibody is a neutralizing control antibody for IL-12 p35, the immunogen is the same as Neutrakine 69029-1-Ig but could not neutralize human IL-12 p35.