• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis of pig heart using 66415-1-Ig (same clone as 66415-1-PBS)

    WB analysis of pig heart using 66415-1-Ig (same clone as 66415-1-PBS)

    pig heart tissue were subjected to SDS PAGE followed by western blot with 66415-1-Ig (AGTR1 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66415-1-PBS in a different storage buffer formulation.

AGTR1 Monoclonal antibody, PBS Only

AGTR1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 66415-1-PBS

产品说明书

CloneNo. 2C5G11

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat, pig

应用

WB, Indirect ELISA

别名

Angiotensin II type-1 receptor, Angiotensin II type 1 receptor, AGTR1B, AGTR1A, AG2S

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

66415-1-PBS targets AGTR1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原 AGTR1 fusion protein Ag14461 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 angiotensin II receptor, type 1
别名 Angiotensin II type-1 receptor, Angiotensin II type 1 receptor, AGTR1B, AGTR1A, AG2S
计算分子量 359 aa, 41 kDa
观测分子量 50 kDa
GenBank蛋白编号BC022447
基因名称 AGTR1
Gene ID (NCBI) 185
RRIDAB_2881787
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP30556
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Angiotensin II (Ang II), the main effector molecule of the renin-angiotensin system, exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1, also named as AT1R), thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone, cardiovascular function, salt and water homeostasis, AGTR1 exerts an indispensable physiological role (PMID: 21600887). AGTR1 has been implicated in diverse aspects of human disease, from the regulation of blood pressure and cardiovascular homeostasis to cancer progression (PMID: 26975580).