FE65 Polyclonal antibody

FE65 Polyclonal Antibody for ELISA
Cat No. 12526-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

ELISA

APBB1, FE65, Protein Fe65, RIR

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy APBB1 Ready-To-Use IHC Kit. APBB1 primary antibody included.

产品信息

12526-1-AP targets FE65 in ELISA applications and shows reactivity with human samples.

经测试应用 ELISA Application Description
经测试反应性 human
免疫原 FE65 fusion protein Ag3221 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
别名 APBB1, FE65, Protein Fe65, RIR
计算分子量 708 aa, 77 kDa
GenBank蛋白编号BC010854
基因名称 APBB1
Gene ID (NCBI) 322
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO00213
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

APBB1 is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression.

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