验证数据展示
Mouse monoclonal antibodies of IgM isotype can be detected with "anti-mouse IgG (H+L)" secondary antibodies.
产品信息
66268-1-PBS targets C1qC in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | C1qC fusion protein Ag10233 种属同源性预测 |
宿主/亚型 | Mouse / IgM |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | complement component 1, q subcomponent, C chain |
别名 | C1Q C, C1qC, C1QG |
计算分子量 | 245 aa, 26 kDa |
观测分子量 | 26 kDa |
GenBank蛋白编号 | BC009016 |
基因名称 | C1QC |
Gene ID (NCBI) | 714 |
RRID | AB_2881653 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Thiophilic affinity chromatograph |
UNIPROT ID | P02747 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1qC which is the C-chain polypeptide of human complement subcomponent C1q.