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- KD/KO Validated
cGAS Polyclonal antibody
cGAS Polyclonal Antibody for IF, IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
IF, IHC, WB, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | HL-60 cells, THP-1 cells |
Positive IHC detected in | human colon cancer tissue, human colon tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Positive IF detected in | HeLa cells |
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:2000-1:16000 |
Immunohistochemistry (IHC) | IHC : 1:400-1:1600 |
Immunofluorescence (IF) | IF : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
26416-1-AP targets cGAS in WB, IP, IHC, IF, ELISA applications and shows reactivity with human samples.
Tested Applications | IF, IHC, WB, ELISA |
Cited Applications | IF, IHC, IP, WB |
Tested Reactivity | human |
Cited Reactivity | human, pig |
Immunogen | cGAS fusion protein Ag23455 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | chromosome 6 open reading frame 150 |
Synonyms | C6orf150, cGAS, Cyclic GMP-AMP synthase, h-cGAS, MB21D1 |
Calculated Molecular Weight | 496 aa, 54 kDa |
Observed Molecular Weight | 58 kDa |
GenBank Accession Number | BC113608 |
Gene Symbol | C6orf150 |
Gene ID (NCBI) | 115004 |
RRID | AB_2880507 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q8N884 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
实验方案
Product Specific Protocols | |
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WB protocol for cGAS antibody 26416-1-AP | Download protocol |
IHC protocol for cGAS antibody 26416-1-AP | Download protocol |
IF protocol for cGAS antibody 26416-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Signal Transduct Target Ther TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion | ||
Cell Poxviruses Evade Cytosolic Sensing through Disruption of an mTORC1-mTORC2 Regulatory Circuit. | ||
Adv Sci (Weinh) PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response. | ||
Nat Commun ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling | ||
Mol Cell CPT1A induction following epigenetic perturbation promotes MAVS palmitoylation and activation to potentiate antitumor immunity
| ||
J Clin Invest Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration. |