Anti-Mouse CD107a / LAMP1 (1D4B), PBS Only

CD107a / LAMP1 Monoclonal Antibody for IF/ICC, FC (Intra)
Cat No. 65050-1-PBS

产品说明书

CloneNo. 1D4B

宿主/亚型

Rat / IgG2a, kappa

种属反应性

mouse

应用

IF/ICC, FC (Intra)

CD107a, Lamp1, Lamp 1, 1D4B

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

65050-1-PBS targets CD107a / LAMP1 in IF/ICC, FC (Intra) applications and shows reactivity with mouse samples.

经测试应用 IF/ICC, FC (Intra) Application Description
经测试反应性 mouse
免疫原 Plasma membrane fraction of mouse embryo NIH/3T3 cell line 种属同源性预测
宿主/亚型 Rat / IgG2a, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 lysosomal-associated membrane protein 1
别名 CD107a, Lamp1, Lamp 1, 1D4B
GenBank蛋白编号BC006785
基因名称 CD107a
Gene ID (NCBI) 16783
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP11438
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

LAMP1 (CD107a) is a heavily glycosylated membrane protein enriched in the lysosomal membrane. LAMP1 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP1 is expressed largely in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane (PMID: 16168398). Elevated LAMP1 expression at the cell surface has also been detected during platelet and granulocytic cell activation, as well as in some tumor cells (PMID: 29085473). LAMP1 functions to provide selectins with carbohydrate ligands. This protein has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis (PMID: 18835598; 29085473; 9426697).

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