验证数据展示
产品信息
60005-1-PBS targets CD2 as part of a matched antibody pair:
MP51114-3: 60005-1-PBS capture and 60781-4-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | WB, IHC, Cytometric bead array, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | CD2 fusion protein Ag0423 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | CD2 molecule |
别名 | LFA-2, LFA 3 receptor, LFA 2, Erythrocyte receptor, CD2 molecule |
计算分子量 | 351 aa, 39 kDa |
观测分子量 | 50 kDa |
GenBank蛋白编号 | BC033583 |
基因名称 | CD2 |
Gene ID (NCBI) | 914 |
ENSEMBL Gene ID | ENSG00000116824 |
RRID | AB_2881350 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P06729 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD2 is a cell surface glycoprotein present on a majority of thymocytes, all mature T cells and subset of NK cells but not on B lymphocytes. It is a pan T-cell marker. CD2 interacts with lymphocyte function-associated antigen (LFA-3/CD58) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.