验证数据展示
产品信息
65575-1-PBS targets CD20 in FC applications and shows reactivity with human samples.
经测试应用 | FC Application Description |
经测试反应性 | human |
免疫原 | Human tonsillar B cells 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | membrane-spanning 4-domains, subfamily A, member 1 |
别名 | |
计算分子量 | 297 aa, 33 kDa |
GenBank蛋白编号 | BC002807 |
基因名称 | CD20 |
Gene ID (NCBI) | 931 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD20 is a 33-37 kDa transmembrane phosphoprotein belonging to the membrane-spanning 4A family (PMID: 3260267; 16785532). CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells (PMID: 7524522). CD20 functions as calcium-permeable cation channel (PMID: 7684739). It is involved in the regulation of B-cell activation, proliferation and differentiation (PMID: 7524522).