验证数据展示
产品信息
66224-1-PBS targets CD43 in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF/ICC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | CD43 fusion protein Ag23595 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | sialophorin |
别名 | Leukocyte sialoglycoprotein, GPL115, GALGP, Galactoglycoprotein, CD43 cytoplasmic tail |
计算分子量 | 400 aa, 43 kDa |
观测分子量 | 115 kDa |
GenBank蛋白编号 | BC012350 |
基因名称 | CD43 |
Gene ID (NCBI) | 6693 |
ENSEMBL Gene ID | ENSG00000197471 |
RRID | AB_2881615 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P16150 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD43, also named leukosialin, sialophorin, galactoglycoprotein, leukocyte sialoglycoprotein, SPN, and is a mucin-like type I transmembrane protein. In humans, it is expressed in haematopoietic cells, including T lymphocytes, monocytes, granulocytes, natural killer cells, platelets, and haematopoietic stem cells, with the exception of mature erythrocytes and B cell subpopulations. The unglycosylated form of CD43 migrates on SDS-PAGE with a molecular weight of 54 kDa (PMID: 2943740), whereas CD43 from different haematopoietic cell lines displays increased molecular weights since it is glycosylated with O-linked chains that differ in core structure and sialylation.