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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 26903-1-AP (same clone as 26903-1-PBS)

    WB analysis using 26903-1-AP (same clone as 26903-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26903-1-AP (CD86 (C-terminal) antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26903-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 26903-1-AP (same clone as 26903-1-PBS)

    IHC staining of human tonsillitis using 26903-1-AP (same clone as 26903-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 26903-1-AP (CD86 (C-terminal) antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26903-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 26903-1-AP (same clone as 26903-1-PBS)

    IHC staining of human tonsillitis using 26903-1-AP (same clone as 26903-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 26903-1-AP (CD86 (C-terminal) antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26903-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 26903-1-AP (same clone as 26903-1-PBS)

    IF Staining of mouse brain using 26903-1-AP (same clone as 26903-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed frozen OCT-embedded mouse brain tissue using CD86 (C-terminal) antibody (26903-1-AP) at dilution of 1:200 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 26903-1-PBS in a different storage buffer formulation.

CD86 (C-terminal) Polyclonal antibody, PBS Only

CD86 (C-terminal) Polyclonal Antibody for WB, IHC, IF-Fro, Indirect ELISA
Cat No. 26903-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF-Fro, Indirect ELISA

别名

CD86, Activation B7 2 antigen, Activation B7-2 antigen, B7 2, B70

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

26903-1-PBS targets CD86 (C-terminal) in WB, IHC, IF-Fro, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF-Fro, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD86 (C-terminal) fusion protein Ag25432 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CD86 molecule
别名 CD86, Activation B7 2 antigen, Activation B7-2 antigen, B7 2, B70
计算分子量 329 aa, 38 kDa
观测分子量 65 kDa
GenBank蛋白编号BC040261
基因名称 CD86
Gene ID (NCBI) 942
ENSEMBL Gene IDENSG00000114013
RRIDAB_2880677
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP42081
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.