COXIV Monoclonal antibody

COXIV Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human and More (2)

Applications

ELISA and More (2)

Conjugate

Unconjugated

CloneNo.

3C7D2

Cat No : 60251-1-Ig

Print datasheet

Synonyms

Cell and organelle markers, COX IV 1, COX4, COX4I1, COXIV, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Mitochondria Marker, Mitochondrial Marker, Mitochondrion Marker



经过测试的应用

Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 60251-1-Ig is COXIV Fusion Protein expressed in E. coli.

Tested Applications ELISA
Cited Applications IF, WB
Tested Reactivity human
Cited Reactivityhuman, mouse, rat
Immunogen COXIV fusion protein Ag20551 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name cytochrome c oxidase subunit IV isoform 1
Synonyms Cell and organelle markers, COX IV 1, COX4, COX4I1, COXIV, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit 4 isoform 1 mitochondrial, Mitochondria Marker, Mitochondrial Marker, Mitochondrion Marker
Calculated Molecular Weight19.6 kDa
Observed Molecular Weight 17-18 kDa
GenBank Accession NumberBC021236
Gene Symbol COX4I1
Gene ID (NCBI) 1327
RRIDAB_2881372
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP13073
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

COX4I1, also named as COX4 and COXIV-1, belongs to the cytochrome c oxidase IV family. It is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. COX4I1 is a marker for mitochondria. It has two isoforms (isoform 1 and 2). Isoform 1(COX4I1) is ubiquitously expressed and isoform 2 is highly expressed in lung tissues. COX4I1 is commonly used as a loading control. This antibody is specific to COX4I1 and do not cross reacts with COX4I2.

实验方案

Product Specific Protocols
IHC protocol for COXIV antibody 60251-1-IgDownload protocol
IF protocol for COXIV antibody 60251-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Autophagy

The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagy

Authors - Bo Zhang
humanIF

Hypertension

Upregulation of Piezo1 (Piezo Type Mechanosensitive Ion Channel Component 1) Enhances the Intracellular Free Calcium in Pulmonary Arterial Smooth Muscle Cells From Idiopathic Pulmonary Arterial Hypertension Patients.

Authors - Jing Liao
mouseIF

Mol Metab

Disruption of STIM1-mediated Ca2+ sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis and lean mass.

Authors - Rebecca J Wilson
mouseIF

Mol Cell Biol

Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis via Upregulation of Mitochondrial Respiratory Chain Complexes.

Authors - Kewei Xie
ratWB,IF

Eur J Histochem

Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function.

Authors - Zhijiang Chen
ratWB

Cells

Parkin-Dependent Mitophagy is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats.

Authors - Qi He