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- KD/KO Validated
ELK1 Polyclonal antibody
ELK1 Polyclonal Antibody for ELISA
验证数据展示
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 3 publications below |
产品信息
14507-1-AP targets ELK1 in WB, ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Immunogen | ELK1 fusion protein Ag5966 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | ELK1, member of ETS oncogene family |
| Synonyms | ELK1 |
| Calculated Molecular Weight | 45 kDa |
| GenBank Accession Number | BC056150 |
| Gene Symbol | ELK1 |
| Gene ID (NCBI) | 2002 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P19419 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
E twenty-six (ETS)-like transcription factor 1, also known as ELK1, is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. It is targeted in the nucleus by three major MAP kinase pathways as well as the CaMKII pathway. phosphorylation of nuclear Elk1 enhances its ability to bind DNA at serum response elements and stimulate transcription of immediate early genes. Elk1 plays important roles in various contexts, including long-term memory formation, drug addiction, Alzheimer's disease, down syndrome, breast cancer, and depression. This antibody got an 62 kd band in western blotting maybe duo to its phosphorylation
发表文章
| Species | Application | Title |
|---|---|---|
Br J Pharmacol L-Hcy-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinemia. | ||
Oncol Lett MicroRNA-326 suppresses the proliferation, migration and invasion of cervical cancer cells by targeting ELK1. |