验证数据展示
| Neutralization | OCI-AML5 |
产品信息
69032-1-Ig targets NeutraKine FLT3 Ligand in ELISA, Neutralization applications and shows reactivity with Human samples.
| 经测试应用 | ELISA, Neutralization Application Description |
| 经测试反应性 | Human |
| 免疫原 | human NeutraKine FLT3 Ligand protein HZ-1151 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | fms-related tyrosine kinase 3 ligand |
| 别名 | FL, Flt3 ligand, Flt3L, FLT3LG, SL cytokine |
| 基因名称 | FLT3 Ligand |
| Gene ID (NCBI) | 2323 |
| RRID | AB_3085333 |
| 偶联类型 | Unconjugated |
| 形式 | Lyophilized Powder |
| 纯化方式 | Protein G purification |
| 储存缓冲液 | Sterile PBS , pH 7.4 |
| 内毒素 | <0.1 EU/μg |
| 复溶 | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| 稳定性与储存 | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
The FMS-related tyrosine kinase 3 (FLT3) ligand (FLT3LG), a growth factor, is mainly derived from lymphocytes in the tumor microenvironment. It binds to FLT3 on DCs to enhance their differentiation and expansion. Therefore, it may assist DCs in tumor antigen presentation and antitumor immune response. In addition, mature DCs express FLT3 and proliferate massively under the trigger of FLT3LG.
This antibody is used to neutralize the bioactivity of FLT3 Ligand.