验证数据展示
产品信息
69532-1-Ig targets FLT3 Ligand in ELISA, Non-Neutralization applications and shows reactivity with Human samples.
| Tested Applications | ELISA, Non-Neutralization Application Description |
| Tested Reactivity | Human |
| Immunogen | human Humankine FLT3 Ligand protein HZ-1151 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | fms-related tyrosine kinase 3 ligand |
| Synonyms | FL, Flt3 ligand, Flt3L, FLT3LG, SL cytokine |
| Gene Symbol | FLT3 Ligand |
| Gene ID (NCBI) | 2323 |
| RRID | AB_3085330 |
| Conjugate | Unconjugated |
| Form | Lyophilized Powder |
| Purification Method | Protein G purification |
| Storage Buffer | Sterile PBS. |
| Endotoxin | <0.1 EU/μg |
| Reconstitution | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
The FMS-related tyrosine kinase 3 (FLT3) ligand (FLT3LG), a growth factor, is mainly derived from lymphocytes in the tumor microenvironment. It binds to FLT3 on DCs to enhance their differentiation and expansion. Therefore, it may assist DCs in tumor antigen presentation and antitumor immune response. In addition, mature DCs express FLT3 and proliferate massively under the trigger of FLT3 Ligand.
This antibody is a neutralizing control antibody for FLT3 Ligand, the immunogen is the same as Neutrakine 69032-Ig but could not neutralize human FLT3 Ligand.