验证数据展示
产品信息
66827-1-PBS targets human IBA1 in IHC, ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, ELISA Application Description |
经测试反应性 | human |
免疫原 | human IBA1 fusion protein Ag28236 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | allograft inflammatory factor 1 |
别名 | AIF1, IBA1, G1, allograft inflammatory factor 1, AIF-1 |
计算分子量 | 17 kDa |
GenBank蛋白编号 | BC009474 |
基因名称 | IBA1 |
Gene ID (NCBI) | 199 |
ENSEMBL Gene ID | ENSG00000204472 |
RRID | AB_2882170 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P55008 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
IBA1 is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Expression of IBA1 is up-regulated in activated microglia following facial nerve axotomy, ischemia, and several brain diseases, thereby implicating it in the activated phenotypes of microglia.