验证数据展示
| Neutralization | HT-29 cell |
产品信息
69007-1-Ig targets NeutraKine® IFN-gamma in Neutralization, ELISA applications and shows reactivity with human samples.
| 经测试应用 | Neutralization, ELISA Application Description |
| 文献引用应用 | Neutralization |
| 经测试反应性 | human |
| 免疫原 | human Humankine IFN-gamma protein HZ-1301 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | IFN gamma |
| 别名 | NeutraKine® IFN Gamma, IFNG, IFN-gamma, IFN γ, IFN gamma |
| 基因名称 | IFNG |
| Gene ID (NCBI) | 3458 |
| ENSEMBL Gene ID | ENSG00000111537 |
| RRID | AB_2882925 |
| 偶联类型 | Unconjugated |
| 形式 | Lyophilized Powder |
| 纯化方式 | Protein A purification |
| 储存缓冲液 | Sterile PBS. |
| 内毒素 | <0.1 EU/μg |
| 复溶 | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| 稳定性与储存 | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.
This antibody can be used to neutralize the bioactivity of Interferon gamma.