• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 66466-1-Ig (same clone as 66466-1-PBS)

    WB analysis using 66466-1-Ig (same clone as 66466-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66466-1-Ig (JAK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 66466-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66466-1-Ig (same clone as 66466-1-PBS)

    IHC staining of human breast cancer using 66466-1-Ig (same clone as 66466-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66466-1-Ig (JAK1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66466-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with JAK1 antibody included
  • IHC staining of human breast cancer using 66466-1-Ig (same clone as 66466-1-PBS)

    IHC staining of human breast cancer using 66466-1-Ig (same clone as 66466-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66466-1-Ig (JAK1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66466-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with JAK1 antibody included
  • Featured Product
  • KD/KO验证

JAK1 Monoclonal antibody, PBS Only

JAK1 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66466-1-PBS

产品说明书

CloneNo. 3H7A8

宿主/亚型

Mouse / IgG2b

种属反应性

human, rat, mouse

应用

WB, IHC, ELISA

别名

JAK 1, JAK1, JAK1A, JAK1B, Janus kinase 1, JTK3, Tyrosine protein kinase JAK1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy JAK1 Ready-To-Use IHC Kit. JAK1 primary antibody included.

产品信息

66466-1-PBS targets JAK1 in WB, IHC, ELISA applications and shows reactivity with human, rat, mouse samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, rat, mouse
免疫原 JAK1 fusion protein Ag17940 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 Janus kinase 1 (a protein tyrosine kinase)
别名 JAK 1, JAK1, JAK1A, JAK1B, Janus kinase 1, JTK3, Tyrosine protein kinase JAK1
计算分子量 1154 aa, 133 kDa
观测分子量 133 kDa
GenBank蛋白编号BC132729
基因名称 JAK1
Gene ID (NCBI) 3716
RRIDAB_2881834
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP23458
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Janus kinase 1(JAK1), is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. JAK1 is essential for signaling for certain type I and type II cytokines. JAK1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body.