验证数据展示
产品信息
66466-1-PBS targets JAK1 in WB, IHC, ELISA applications and shows reactivity with human, rat, mouse samples.
Tested Applications | WB, IHC, ELISA Application Description |
Tested Reactivity | human, rat, mouse |
Immunogen | JAK1 fusion protein Ag17940 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | Janus kinase 1 (a protein tyrosine kinase) |
Synonyms | JAK 1, JAK1, JAK1A, JAK1B, Janus kinase 1, JTK3, Tyrosine protein kinase JAK1 |
Calculated Molecular Weight | 1154 aa, 133 kDa |
Observed Molecular Weight | 133 kDa |
GenBank Accession Number | BC132729 |
Gene Symbol | JAK1 |
Gene ID (NCBI) | 3716 |
RRID | AB_2881834 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P23458 |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Janus kinase 1(JAK1), is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. JAK1 is essential for signaling for certain type I and type II cytokines. JAK1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body.