MAGEC2 Polyclonal antibody

MAGEC2 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 10280-1-AP

Print datasheet

Synonyms

Cancer/testis antigen 10, CT10, HCA587, MAGE C2 antigen, MAGE E1 antigen, MAGEC2, MAGEE1, melanoma antigen family C, 2, Melanoma associated antigen C2



经过测试的应用

Positive IHC detected inhuman liver cancer tissue, human breast cancer tissue, human malignant melanoma tissue, human testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy MAGEC2 Ready-To-Use IHC Kit. MAGEC2 primary antibody included.

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 2 publications below

产品信息

10280-1-AP targets MAGEC2 in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Cited ApplicationsIHC
Tested Reactivity human
Cited Reactivityhuman
Immunogen MAGEC2 fusion protein Ag0418 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name melanoma antigen family C, 2
Synonyms Cancer/testis antigen 10, CT10, HCA587, MAGE C2 antigen, MAGE E1 antigen, MAGEC2, MAGEE1, melanoma antigen family C, 2, Melanoma associated antigen C2
Calculated Molecular Weight 373 aa, 41 kDa
GenBank Accession NumberBC005891
Gene Symbol MAGEC2
Gene ID (NCBI) 51438
RRIDAB_2138540
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UBF1
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Melanoma antigen family C, 2(MAGEC2, synonyms: CT10, HCA587, MAGEE1, MGC13377) is related to members of the MAGEC gene family. MAGEC2 is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and other MAGEC genes are clustered on chromosome Xq26-q27.

实验方案

Product Specific Protocols
WB protocol for MAGEC2 antibody 10280-1-APDownload protocol
IHC protocol for MAGEC2 antibody 10280-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

PLoS One

γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo.

Authors - Sharma Anu A
humanIHC

Hum Pathol

Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers.

Authors - Annikka Weissferdt

Laryngoscope Investig Otolaryngol

The expression of the cancer testis antigen MAGE A4: A favorable prognostic biomarker in salivary gland carcinomas related to low tumor grading.

Authors - Domenic Vital