ASK1 Polyclonal antibody

ASK1 Polyclonal Antibody for ELISA
Cat No. 14385-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat and More (1)

应用

ELISA and More (1)

ASK 1, ASK1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


发表文章中的应用

WBSee 4 publications below

产品信息

14385-1-AP targets ASK1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse, rat
文献引用反应性human, rat, monkey
免疫原 ASK1 fusion protein Ag5818 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 mitogen-activated protein kinase kinase kinase 5
别名 ASK 1, ASK1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5
计算分子量 155 kDa
GenBank蛋白编号BC054503
基因名称 ASK1
Gene ID (NCBI) 4217
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ99683
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38.

发表文章

SpeciesApplicationTitle
ratWB

J Mol Cell Cardiol

Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.

Authors - Na Zhao
monkeyWB

Cell Microbiol

\Non-haemolytic enterotoxin (Nhe) of Bacillus cereus induces apoptosis in Vero cells.

Authors - Xiaoye Liu
humanWB

Life Sci

Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells.

Authors - Chen Xiaoping X
ratWB

J Agric Food Chem

Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus

Authors - Yujie Zhao
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