验证数据展示
发表文章中的应用
| WB | See 4 publications below |
产品信息
14385-1-AP targets ASK1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, rat, monkey |
| Immunogen | ASK1 fusion protein Ag5818 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | mitogen-activated protein kinase kinase kinase 5 |
| Synonyms | ASK 1, ASK1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5 |
| Calculated Molecular Weight | 155 kDa |
| GenBank Accession Number | BC054503 |
| Gene Symbol | ASK1 |
| Gene ID (NCBI) | 4217 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q99683 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species (ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase (JNK) and p38.
发表文章
| Species | Application | Title |
|---|---|---|
J Mol Cell Cardiol Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction. | ||
Cell Microbiol \Non-haemolytic enterotoxin (Nhe) of Bacillus cereus induces apoptosis in Vero cells. | ||
Life Sci Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells. | ||
J Agric Food Chem Ginsenoside F4 Alleviates Skeletal Muscle Insulin Resistance by Regulating PTP1B in Type II Diabetes Mellitus |