NeutraControl IL-27 Monoclonal antibody

NeutraControl IL-27 Monoclonal Antibody for ELISA, Non-Neutralization
Cat No. 69534-1-Ig

产品说明书

CloneNo. 2F8E2

宿主/亚型

Mouse / IgG2a

种属反应性

Human

应用

ELISA, Non-Neutralization

IL 27, IL 27 A, IL 27 subunit alpha, IL 27A, IL27, IL27 A, IL27A, IL27p28, IL30, interleukin 27, Interleukin 27 subunit alpha, p28

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


产品信息

69534-1-Ig targets IL-27 in ELISA, Non-Neutralization applications and shows reactivity with Human samples.

经测试应用 ELISA, Non-Neutralization Application Description
经测试反应性 Human
免疫原 human Humankine IL-27 protein HZ-1275 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 27
别名 IL 27, IL 27 A, IL 27 subunit alpha, IL 27A, IL27, IL27 A, IL27A, IL27p28, IL30, interleukin 27, Interleukin 27 subunit alpha, p28
基因名称 IL-27
Gene ID (NCBI) 246778
RRIDAB_3670461
偶联类型 Unconjugated
形式 Lyophilized Powder
纯化方式Protein A purification
UNIPROT IDQ8NEV9
储存缓冲液 Sterile PBS , pH 7.4
内毒素<0.1 EU/μg
复溶This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
稳定性与储存Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

背景介绍

IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.

This antibody is a neutralizing control antibody for IL-27, the immunogen is the same as Neutrakine 69034-1-Ig but could not neutralize human IL-27.

Loading...