验证数据展示
| Neutralization |
产品信息
69017-1-Ig targets NeutraKine® Cystatin C in ELISA, Neutralization applications and shows reactivity with Human samples.
| 经测试应用 | ELISA, Neutralization Application Description |
| 经测试反应性 | Human |
| 免疫原 | human Humankine Cystatin C protein HZ-1211 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | cystatin C |
| 别名 | ARMD11, CST3, Cystatin 3, cystatin C, Gamma trace, NeutraKine® Cystatin C, Post gamma globulin |
| 基因名称 | Cystatin C |
| Gene ID (NCBI) | 1471 |
| RRID | AB_2918837 |
| 偶联类型 | Unconjugated |
| 形式 | Lyophilized Powder |
| 纯化方式 | Protein G purification |
| 储存缓冲液 | Sterile PBS , pH 7.4 |
| 内毒素 | <0.1 EU/μg |
| 复溶 | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| 稳定性与储存 | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. It is also used as an emerging biomarker in cardiovascular disease. Cystatin C is involved in a variety of inflammatory reactions. The concentration of serum cystatin C has also been shown to be unaltered in certain inflammatory conditions or other disorders of metabolism. The plasma level of serum cystatin C can be expressed as its level of generation from cells and diet and its subsequent elimination through the gut, liver, and kidneys.
This antibody can be used to neutralize the bioactivity of Cystatin C.