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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (PR antibody) at dilution of 1:9900 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PR antibody included
  • IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (PR antibody) at dilution of 1:9900 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PR antibody included
  • IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (PR antibody) at dilution of 1:10000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PR antibody included

PR Monoclonal antibody, PBS Only

PR Monoclonal Antibody for IHC, ELISA
Cat No. 66300-1-PBS
CloneNo. 3D1D12

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IHC, ELISA

Synonyms

PGR, PRGR, NR3C3, 3D1D12

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PR Ready-To-Use IHC Kit. PR primary antibody included.

产品信息

66300-1-PBS targets PR in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen PR fusion protein Ag22992 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name progesterone receptor
Synonyms PGR, PRGR, NR3C3, 3D1D12
Calculated Molecular Weight 933 aa, 99 kDa
GenBank Accession NumberNM_000926
Gene Symbol Progesterone Receptor
Gene ID (NCBI) 5241
RRIDAB_2881683
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP06401
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.