PR Monoclonal antibody, PBS Only

PR Monoclonal Antibody for IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

CloneNo.

3D1D12

Cat no : 66300-1-PBS

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Synonyms

NR3C3, PGR, PR, progesterone receptor



Planning an IHC experiment? We recommend our IHCeasy PR Ready-To-Use IHC Kit. PR primary antibody included.

产品信息

66300-1-PBS targets PR in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen PR fusion protein Ag22992 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name progesterone receptor
Synonyms NR3C3, PGR, PR, progesterone receptor
Calculated Molecular Weight 933 aa, 99 kDa
GenBank Accession NumberNM_000926
Gene Symbol Progesterone Receptor
Gene ID (NCBI) 5241
RRIDAB_2881683
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP06401
Storage Buffer PBS only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PGR, also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.