验证数据展示
产品信息
67317-1-PBS targets TLR8 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human samples.
Tested Applications | WB, IHC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | Human |
Immunogen | TLR8 fusion protein Ag16566 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | toll-like receptor 8 |
Synonyms | CD288, TLR8, toll like receptor 8 |
Calculated Molecular Weight | 1041 aa, 120 kDa |
Observed Molecular Weight | 120 kDa |
GenBank Accession Number | BC101075 |
Gene Symbol | TLR8 |
Gene ID (NCBI) | 51311 |
RRID | AB_2882577 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9NR97 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Toll-like receptors (TLRs) are a group of pathogen recognition receptors (PRRs) that can be divided into two subfamilies depending on their subcellular localization(PMID: 32268138). Toll-like receptor 8 (TLR8), a sensor for pathogen-derived single-stranded RNA (ssRNA), binds to uridine (Uri) and ssRNA to induce defense responses (PMID:30535046). TLR8 proteins were expressed in spleen, epididymal sperm, testicular sperm cells, and Leydig cells but were weak in Sertoli cells. It can identify two isoforms,120 and 122 kDa.