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验证数据展示

  • WB analysis using 60333-1-Ig (same clone as 60333-1-PBS)

    WB analysis using 60333-1-Ig (same clone as 60333-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60333-1-Ig (TMEM106B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60333-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    WB analysis of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    WB result of TMEM106B antibody (60333-1-Ig; 1:2000; room temperature for 1.5 hours) with wild-type and TMEM106B knockout HeLa cells. This data was developed using the same antibody clone with 60333-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    IP experiment of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    IP result of anti-TMEM106B (IP:60333-1-Ig, 5ug; Detection:60333-1-Ig 1:500) with HeLa cells lysate 1720 ug. This data was developed using the same antibody clone with 60333-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TMEM106B Monoclonal antibody, PBS Only

TMEM106B Monoclonal Antibody for WB, IP, Indirect ELISA
Cat No. 60333-1-PBS

产品说明书

CloneNo. 5D1F8

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IP, Indirect ELISA

别名

TMEM106B, transmembrane protein 106B

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60333-1-PBS targets TMEM106B in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原 TMEM106B fusion protein Ag21448 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 transmembrane protein 106B
别名 TMEM106B, transmembrane protein 106B
计算分子量 31 kDa
观测分子量 ~40 kDa
GenBank蛋白编号BC033901
基因名称 TMEM106B
Gene ID (NCBI) 54664
RRIDAB_2881442
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9NUM4
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TMEM106B is a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS), like FTLD-TDP, is characterized by pathological TDP-43 inclusions. TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confer genetic susceptibility by increasing gene expression.