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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 67492-1-Ig (same clone as 67492-1-PBS)

    WB analysis using 67492-1-Ig (same clone as 67492-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67492-1-Ig (TRIM5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67492-1-PBS in a different storage buffer formulation.

TRIM5 Monoclonal antibody, PBS Only

TRIM5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67492-1-PBS

产品说明书

CloneNo. 1H1G9

宿主/亚型

Mouse / IgG2b

种属反应性

Human

应用

WB, Indirect ELISA

别名

RING finger protein 88, RNF88, TRIM5, TRIM5alpha, tripartite motif containing 5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67492-1-PBS targets TRIM5 in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 TRIM5 fusion protein Ag30059 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 tripartite motif-containing 5
别名 RING finger protein 88, RNF88, TRIM5, TRIM5alpha, tripartite motif containing 5
计算分子量 493 aa, 56 kDa
观测分子量 56 kDa
GenBank蛋白编号BC021258
基因名称 TRIM5
Gene ID (NCBI) 85363
RRIDAB_2882717
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9C035
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRIM5 belongs to the large tripartite motif protein family, members of which typically are composed of 3 zinc-binding domains, a RING, unique B-box type 1 and B-box type 2 domains, followed by a coiled-coil (CC) region. TRIM proteins use homomultimerization to identify specific cell compartments. TRIM5 promotes innate immune signaling and that this activity is amplified by retroviral infection and interaction with the capsid lattice. TRIM5 has 6 variants termed alpha, beta, gamma, delta, epsilon, and iota with the MW of 56 kDa, 46 kDa, 40 kDa, 37 kDa, 31 kDa and 29 kDa. TRIM5 can form homodimers (~70 kDa) and homotrimers (90-160 kDa).