TWIST1 Polyclonal antibody

TWIST1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat no : 18125-1-AP

Print datasheet

Synonyms

ACS3, bHLHa38, BPES2, BPES3, H twist, SCS, TWIST, twist homolog 1 (Drosophila), Twist related protein 1, TWIST1



经过测试的应用

Positive WB detected inPC-3 cells, MCF-7 cells, SGC-7901 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 18125-1-AP is TWIST1 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF, IHC
Tested Reactivity human
Cited Reactivityhuman, mouse, rat
Immunogen TWIST1 fusion protein Ag12700 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name twist homolog 1 (Drosophila)
Synonyms ACS3, bHLHa38, BPES2, BPES3, H twist, SCS, TWIST, twist homolog 1 (Drosophila), Twist related protein 1, TWIST1
Calculated Molecular Weight 202 aa, 21 kDa
Observed Molecular Weight 22 kDa, 28 kDa, 45-60 kDa
GenBank Accession NumberBC036704
Gene Symbol TWIST1
Gene ID (NCBI) 7291
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ15672
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TWIST1, a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. It is also implicated in tumorigenesis, invasion and metastasis. TWIST1 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).

实验方案

Product Specific Protocols
WB protocol for TWIST1 antibody 18125-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
human,mouseIHC,IF

Theranostics

Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis.

Authors - Limin Liu
humanWB

Int J Biochem Cell Biol

Blue light emitting diodes irradiation causes cell death in colorectal cancer by inducing ROS production and DNA damage.

Authors - Gege Yan
humanWB

Cancer Lett

Downregulation of ACE2/Ang-(1-7)/Mas axis promotes breast cancer metastasis by enhancing store-operated calcium entry.

Authors - Changhui Yu
humanWB,IHC

Int J Cancer

Down-regulation of KIAA1199/CEMIP by miR-216a suppresses tumor invasion and metastasis in colorectal cancer.

Authors - Dejun Zhang
humanWB

Sci Rep

Correlations between TBL1XR1 and recurrence of colorectal cancer.

Authors - Hongda Liu
mouseWB

Sci Rep

Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.

Authors - Yu Liang