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NeutraKine® Thrombin-Coagulation FactorII Monoclonal antibody

NeutraKine® Thrombin-Coagulation FactorII Monoclonal Antibody for Neutralization, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

Neutralization, ELISA

Conjugate

Unconjugated

CloneNo.

2G3G10

Cat no : 69014-1-Ig

Print datasheet

Synonyms

Coagulation factor II, F2, EC:3.4.21.5, Activation peptide fragment 2, Activation peptide fragment 1

验证数据展示

  • Neutralization experiment of NeutraKine® Thrombin-Coagulation FactorII using 69014-1-Ig

    Neutralization experiment of NeutraKine® Thrombin-Coagulation FactorII using 69014-1-Ig

    Recombinant human Thrombin (Cat.NO. HZ-3010) catalyzes Spectrozyme PL to form chromophore (monitored absorbance at 405 nm) in a dose dependent manner (left pannel). The activity of Thrombin (400ng/mL HZ-3010) was inihibited by serial dose of anti-Thrombin monoclonal antibody 69014-1-Ig (right pannel). The typically ND50 is 5-20 μg/mL.

Neutralization

产品信息

69014-1-Ig targets NeutraKine® Thrombin-Coagulation FactorII in Neutralization, ELISA applications and shows reactivity with human samples.

Tested Applications Neutralization, ELISA Application Description
Tested Reactivity human
Immunogen human Humankine Thrombin-Coagulation FactorII protein HZ-3010 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name coagulation factor II (prothrombin)
Synonyms Coagulation factor II, F2, EC:3.4.21.5, Activation peptide fragment 2, Activation peptide fragment 1
Gene Symbol F2
Gene ID (NCBI) 2147
RRIDAB_2882932
Conjugate Unconjugated
Form Lyophilized Powder
Purification MethodProtein G purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

背景介绍

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Coagulation Factor II, also known as prothrombin or factor II, is one of the components of this chain of plasma proteins involved in blood coagulation. Prothrombin is the precursor of thrombin, which is essential in the processes of hemostasis and thrombosis.

This antibody can be used to neutralize the bioactivity of Thrombin-Coagulation FactorII.