UBQLN2 Polyclonal antibody

UBQLN2 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat and More (1)

Applications

IF, IHC, WB, ELISA and More (1)

Conjugate

Unconjugated

Cat No : 23449-1-AP

Print datasheet

Synonyms

CHAP1, CHAP1/DSK2, Dsk2, DSK2 homolog, hPLIC 2, HRIHFB2157, LIC 2, N4BP4, PLIC 2, PLIC2, RIHFB2157, ubiquilin 2, Ubiquilin-2, UBQLN2



经过测试的应用

Positive WB detected inrat brain tissue, HEK-293 cells, HepG2 cells
Positive IHC detected inhuman testis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

23449-1-AP targets UBQLN2 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, rat samples.

Tested Applications IF, IHC, WB, ELISA
Cited Applications IF, IP, WB
Tested Reactivity human, rat
Cited Reactivityhuman, mouse
Immunogen UBQLN2 fusion protein Ag20149 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name ubiquilin 2
Synonyms CHAP1, CHAP1/DSK2, Dsk2, DSK2 homolog, hPLIC 2, HRIHFB2157, LIC 2, N4BP4, PLIC 2, PLIC2, RIHFB2157, ubiquilin 2, Ubiquilin-2, UBQLN2
Calculated Molecular Weight 624 aa, 66 kDa
Observed Molecular Weight 66-70 kDa
GenBank Accession NumberBC069237
Gene Symbol UBQLN2
Gene ID (NCBI) 29978
RRIDAB_2879282
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UHD9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

实验方案

Product Specific Protocols
WB protocol for UBQLN2 antibody 23449-1-APDownload protocol
IHC protocol for UBQLN2 antibody 23449-1-APDownload protocol
IF protocol for UBQLN2 antibody 23449-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Brain

Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies

Authors - Charlotte Gineste

Hum Mol Genet

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

Authors - Aline Dubos
mouseIF

Brain Pathol

Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.

Authors - Nicole R Higgins
WB

J Neurochem

Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.

Authors - Yuxing Xia
humanWB,IF,IP

F1000Res

The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence

Authors - Ian McDowell
  • KO Validated
WB

bioRxiv

Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Authors - Thuy P Dao