WNT2 Polyclonal antibody
WNT2 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
发表文章中的应用
| WB | See 5 publications below |
| IHC | See 1 publications below |
产品信息
11160-1-AP targets WNT2 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB, IHC |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Immunogen | WNT2 fusion protein Ag1641 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | wingless-type MMTV integration site family member 2 |
| Synonyms | Int 1 like protein 1, Int 1 related protein, INT1L1, IRP, Protein Wnt 2, WNT2 |
| Calculated Molecular Weight | 40 kDa |
| GenBank Accession Number | BC029854 |
| Gene Symbol | WNT2 |
| Gene ID (NCBI) | 7472 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P09544 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Wnt2 is a secreted glycoprotein that is one of the canonical Wnt ligands. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt2 is known to directly regulate β-catenin activity, the key player in proliferation and inflammation. Recently, studies have demonstrated that Wnt2 is overexpressed in various human cancers, including esophageal, gastric, colorectal, breast, lung, cervical, and malignant glioma.
发表文章
| Species | Application | Title |
|---|---|---|
J Biol Chem HBP1-mediated regulation of p21 through Mdm2/p53 and TCF4/EZH2 pathways and its impact on cell senescence and tumorigenesis. | ||
PLoS One Plasma miR-199a-5p is increased in neutrophilic phenotype asthma patients and negatively correlated with pulmonary function. | ||
Int J Oncol CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells. | ||
Oncol Rep RNA-binding motif protein 5 negatively regulates the activity of Wnt/β-catenin signaling in cigarette smoke-induced alveolar epithelial injury. | ||
Neurol Res Wnt signaling pathway is involved in the pathogenesis of amyotrophic lateral sclerosis in adult transgenic mice. |