验证数据展示
产品信息
60200-1-PBS targets ZAP70 as part of a matched antibody pair:
MP51134-1: 60200-3-PBS capture and 60200-1-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | WB, IHC, IF-P, Cytometric bead array, Indirect ELISA Application Description |
经测试反应性 | human, mouse, pig |
免疫原 | ZAP70 fusion protein Ag7943 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | zeta-chain (TCR) associated protein kinase 70kDa |
别名 | STD, SRK, EC:2.7.10.2, 70 kDa zeta-chain associated protein, 70 kDa zeta associated protein |
计算分子量 | 70 kDa |
观测分子量 | 70 kDa |
GenBank蛋白编号 | BC039039 |
基因名称 | ZAP70 |
Gene ID (NCBI) | 7535 |
ENSEMBL Gene ID | ENSG00000115085 |
RRID | AB_10944567 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P43403 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Zeta-associated protein (ZAP)-70, a member of the Syk family of tyrosine kinases, plays an important role in T-cell receptor signaling, natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.