- HEK293 expressed
- Endotoxin-free
- Animal-component free
HumanKine® recombinant human FGFbasic-TS protein
Activity
0.4-2.5 ng/mL EC50 in NIH3T3 cells in defined Media
Specific Activity
1.15 x 107 IU/mg
Species Reactivity
human,mouse,rat
Purity
>95%
Cat No : HZ-1285
Synonyms
Basic fibroblast growth factor, BFGF, FGF basic, FGF basic-TS, FGF2, FGFB, FGFbasic, FGFbasic-TS, HBGF 2
Validation Data Gallery
Technical Specifications
GeneID | 2247 |
Species | Human |
Expression | HEK293 |
Activity | 0.4-2.5 ng/mL EC50 in NIH3T3 cells in defined Media |
Specific Activity | 1.15 x 107 IU/mg |
Purity | >95% |
Endotoxin | <1 EU/µg |
Accession Number | P09038 |
Molecular Mass | 17 kDa, monomer, non-glycosylated |
Formulation | 1x PBS, See Certificate of Analysis for details |
Species Reactivity | human,mouse,rat |
Stability and Reconstitution
Stability and Storage | Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
Background
Basic Fibroblast growth factor (FGFbasic), also known as bFGF, FGF2, FGF-β or HBGF-2, belongs to the FGF family. FGFbasic is involved in a number of biological processes including embryonic development and differentiation, neuron differentiation, survival, and regeneration, and the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin (PMID 3272178, 3316527). FGFbasic is critical for human embryonic stem cells to remain in an undifferentiated state during cell culture (PMID 15782187).
Synonyms
Basic fibroblast growth factor, BFGF, FGF basic, FGF basic-TS, FGF2, FGFB, FGFbasic, FGFbasic-TS, HBGF 2
Publications
Species | Title |
---|---|
Cell Stem Cell A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. | |
Cell Res Visualization of aging-associated chromatin alterations with an engineered TALE system. | |
Mol Psychiatry Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes. | |
J Clin Invest Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism. | |
Nat Commun Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. |