• HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human IL-7 protein

Activity

0.1-1.4 ng/mL EC50

Specific Activity

>7.00x107 IU/mg

Species Reactivity

human,mouse,rat

Purity

>95%

Cat No : HZ-1281

Print datasheet

Synonyms

IL 7, IL7, IL-7, interleukin 7



Technical Specifications

GeneID 3574
Species Human
Expression HEK293
Activity 0.1-1.4 ng/mL EC50
Specific Activity>7.00x107 IU/mg
Purity >95%
Endotoxin<1 EU/μg
Accession NumberP10168
Molecular Mass 19, 25, and 30 kDa, monomer, glycosylated
Formulation 1x PBS, See Certificate of Analysis for details
Species Reactivity human,mouse,rat

Stability and Reconstitution

Stability and StorageProduct FormTemperature ConditionsStorage Time
(From Date of Receipt)
Lyophilized-20°C to -80°CUntil Expiry Date
LyophilizedRoom Temperature2 weeks
Reconstituted as per CofA-20°C to -80°C6 months
Reconstituted as per CofA4°C1 week
Avoid repeated freeze-thaw cycles.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA).

Background

Interleukin-7 (IL7) is a cytokine involved in B and T cell development. It plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes and is a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Furthermore, IL7 can improve the antiviral function and expansion of natural killer (NK) cells and regulate the development and differentiation of dendritic cells. IL7 has also been reported as a regulator of the development of central nervous system and myogenesis and skeletal muscle cell migration (PMID: 29663382; 29655570; 29449560)

Synonyms

IL 7, IL7, IL-7, interleukin 7

Publications

SpeciesTitle
human

Front Oncol

Combination of 4-1BB and DAP10 promotes proliferation and persistence of NKG2D(bbz) CAR-T cells

Authors - Cheng Wei

Biochem J

Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation

Authors - Rayner M L Queiroz
rat

Heliyon

Astragalus regulates the intestinal immune response during sepsis by mediating ILC3 proliferation through RORγt

Authors - Jin Li